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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -CDC6 (S106) (Cell division control protein 6 homolog, CDC6-related protein, p62(cdc6), HsCDC6, HsCDC18, CDC6, CDC18L)

Anti -CDC6 (S106) (Cell division control protein 6 homolog, CDC6-related protein,
p62(cdc6), HsCDC6, HsCDC18, CDC6, CDC18L)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
Human Cdc6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Catalog #033605
ApplicationsSuitable for use in Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenCDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S106 of human CDC6.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCell division control protein 6 homolog, CDC6-related protein, p62(cdc6), HsCDC6, HsCDC18, CDC6, CDC18L


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