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You are here:Home » Antibodies » Abs to Cadherin » Anti -CDH4, NT (CDH4, Cadherin-4, Retinal cadherin)

Anti -CDH4, NT (CDH4, Cadherin-4, Retinal cadherin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC IF
CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
Catalog #033634
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:10-50
Immunofluorescence 1:10-50
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by peptide immunoaffinity chromatography.
ImmunogenCDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182~211 amino acids from the N-terminal region of human CDH4.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCDH4, Cadherin-4, Retinal cadherin


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