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You are here:Home » Antibodies » Antibodies-Cell Markers » Anti -CEACAM7, ID (CEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2)

Anti -CEACAM7, ID (CEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule
7, Carcinoembryonic antigen CGM2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
CEA-related cell adhesion molecule 7 (CEACAM7,CGM2) belongs to the carcinoembryonic antigen (CEA) family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constantlike A domain.
Catalog #033746
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A and peptide affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 112-140 in the central region of human CEACAM7, UniProt Accession #Q14002; NP_008821.1.
SpecificityRecognizes human CEACAM7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2


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