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033906 Rabbit Anti-CIAO1, ID (CIAO1, WDR39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
O76071; Q32PJ6
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_004795.1
Gene ID
9391
Gene #
CIAO1
Shipping Temp
Blue Ice
Storage Temp
-20°C
CIAO1, WDR39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39

CIAO1 is an essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1.

Applications
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 155-183 in the central region of human CIAO1. Species sequence homology: bovine
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human CIAO1.
References
1. Srinivasan, V., et al. Structure 15(10):1246-1257(2007) 2. Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : 3.Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006) 4. Johnstone, R.W., et al. J. Biol. Chem. 273(18):10880-10887(1998)
USBio References
No references available
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