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You are here:Home » Antibodies » Abs to Ion Channel » Anti -CLCN2, CT (Chloride channel protein 2, ClC-2)

Anti -CLCN2, CT (Chloride channel protein 2, ClC-2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
CLCN2 is a voltage-gated chloride channel, a class of proteins that have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This protein is ubiquitously expressed, with moderate expression in aortic and coronary vascular smooth muscle cells and low levels expressed in aortic endothelial cells. Defects in CLCN2 may be the cause of epilepsy with grand mal seizures on awakening, childhood absence epilepsy type 3, and juvenile absence epilepsy. Single nucleotide polymorphisms (SNPs) of CLCN2 may also at as potential modifiers of cystic fibrosis disease severity.
Catalog #033948
ApplicationsSuitable for use in ELISA
Recommended DilutionELISA: 1:1,000
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration0.25mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenCLCN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 869~898 amino acids from the C-terminal region of human CLCN2.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesChloride channel protein 2, ClC-2


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