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You are here:Home » Antibodies » Abs to Collagen » Anti -COL18A1, ID (COL18A1, Collagen alpha-1(XVIII) chain, Endostatin)

Anti -COL18A1, ID (COL18A1, Collagen alpha-1(XVIII) chain, Endostatin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
COL18A1 is the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure.
Catalog #034084
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenCOL18A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1314-1343 amino acids from the Central region of human COL18A1.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCOL18A1, Collagen alpha-1(XVIII) chain, Endostatin


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