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034098 Rabbit Anti-COL8A1, NT (COL8A1, C3orf7, Collagen alpha-1(VIII) chain, Endothelial collagen, Vastatin)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P27658
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001841.2; NP_065084.2
Gene ID
1295
Gene #
COL8A1
Shipping Temp
Blue Ice
Storage Temp
-20°C
COL8A1, C3orf7, Collagen alpha-1(VIII) chain, Endothelial collagen, Vastatin

This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 62-89 in the N-terminal region of human COL8A1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human COL8A1.
References
1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) 3. Neale, B.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7395-7400(2010) 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 5. Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009).
USBio References
No references available
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