COPZ2 encodes a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. COPZ2 is similar to a related family member, and the two encoded proteins form distinct isotypes of the coatomer protein complex.
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