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034160 Rabbit Anti-CPB1, NT (CPB1, CPB, PCPB, Carboxypeptidase B, Pancreas-specific protein)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P15086
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IF IHC WB
Crossreactivity
Hu
Accession #
NP_001862.2
Gene ID
1360
Gene #
CPB1
Shipping Temp
Blue Ice
Storage Temp
-20°C
CPB1, CPB, PCPB, Carboxypeptidase B, Pancreas-specific protein

Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Indirect Flow Cytometry: 1:10-50 Immunofluorescence: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human CPB1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :|Pantoja-Uceda, D., et al. Biochemistry 47(27):7066-7078(2008)|Guimaraes, A.H., et al. Arterioscler. Thromb. Vasc. Biol. 27(10):2157-2162(2007)|Barbosa Pereira, P.J., et al. J. Mol. Biol. 321(3):537-547(2002)|Aloy, P., et al. Biol. Chem. 379(2):149-155(1998)
USBio References
No references available
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