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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -CYP2C19, NT (CYP2C19, Cytochrome P450 2C19, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome P450-11A, Cytochrome P450-254C, Mephenytoin 4-hydroxylase)

Anti -CYP2C19, NT (CYP2C19, Cytochrome P450 2C19, (R)-limonene 6-monooxygenase,
(S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome
P450-11A, Cytochrome P450-254C, Mephenytoin 4-hydroxylase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH IF
CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
Catalog #034433
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:50-100
Immunofluorescence: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
ImmunogenCYP2C19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88~117 amino acids from the N-terminal region of human CYP2C19.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCYP2C19, Cytochrome P450 2C19, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome P450-11A, Cytochrome P450-254C, Mephenytoin 4-hydroxylase


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