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You are here:Home » Antibodies » Abs to Disease Markers » Anti -DCT, NT (DCT, TYRP2, L-dopachrome tautomerase, L-dopachrome Delta-isomerase, Tyrosinase-related protein 2)

Anti -DCT, NT (DCT, TYRP2, L-dopachrome tautomerase, L-dopachrome Delta-isomerase,
Tyrosinase-related protein 2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Catalog #034517
Involved in regulating eumelanin and phaeomelanin levels. The tyrosinase family in vertebrates consists of three related melanogenic enzymes tryrosinase, tyrosinase-related protein-1 (TRP-1) and tyrosinase-related protein-2 (TRP-2). These proteins control melanin production in pigment cells and play a crucial role in determining vertebrate coloration and are expressed by melanoma cells, normal melanocytes and nevi, but not carcinomas or sarcomas.
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 62-89 in the N-terminal region of human DCT, UniProt Accession #P40126.
SpecificityRecognizes human DCT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDCT, TYRP2, L-dopachrome tautomerase, L-dopachrome Delta-isomerase, Tyrosinase-related protein 2


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