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You are here:Home » Antibodies » Antibodies-Enzymes, Decarboxylase » Anti -DDC, NT (DDC, AADC, Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase)

Anti -DDC, NT (DDC, AADC, Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC IF
This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.
Catalog #034530
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Immunofluorescence: 1:10-1:50
Immunohistochemistry: 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 32-61 in the N-terminal region of human DDC, UniProt Accession #P20711.
SpecificityRecognizes human DDC. Species crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDDC, AADC, Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase


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