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034703 Rabbit Anti-DNAJB6, ID (DNAJB6, HSJ2, MRJ, MSJ1, DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, MSJ-1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_490647.1; O75190; NP_005485.1
Gene ID
10049
Gene #
DNAJB6
Shipping Temp
Blue Ice
Storage Temp
-20°C
DNAJB6, HSJ2, MRJ, MSJ1, DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, MSJ-1

This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DNAJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-247 amino acids from the Central region of human DNAJB6.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Mitra, A., et al. J. Biol. Chem. 285(32):24686-24694(2010)|Edo De Bock, C., et al. Int. J. Oncol. 36(5):1155-1163(2010)|Hageman, J., et al. Mol. Cell 37(3):355-369(2010)|Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :|Dey, S., et al. Mol. Cell. Biochem. 322 (1-2), 137-142 (2009) :
USBio References
No references available
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