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You are here:Home » Antibodies » Abs to Cadherin » Anti -DSC3, CT (DSC3, CDHF3, DSC4, Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP)

Anti -DSC3, CT (DSC3, CDHF3, DSC4, Desmocollin-3, Cadherin family member 3, Desmocollin-4,
HT-CP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
The protein encoded by this gene is a calcium-dependent_x000D_ glycoprotein that is a member of the desmocollin subfamily of the_x000D_ cadherin superfamily. These desmosomal family members, along with_x000D_ the desmogleins, are found primarily in epithelial cells where they_x000D_ constitute the adhesive proteins of the desmosome cell-cell_x000D_ junction and are required for cell adhesion and desmosome_x000D_ formation. The desmosomal family members are arranged in two_x000D_ clusters on chromosome 18, occupying less than 650 kb combined._x000D_ Alternative splicing results in two transcript variants encoding_x000D_ distinct isoforms.
Catalog #034809
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenDSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-850 amino acids from the C-terminal region of human DSC3.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDSC3, CDHF3, DSC4, Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP


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