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You are here:Home » Antibodies » Antibodies-Cadherin » Anti -DSG1, ID (DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen)

Anti -DSG1, ID (DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal
glycoprotein 1, Pemphigus foliaceus antigen)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Catalog #034827
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 471-499 in the central region of human DSG1, UniProt Accession #Q02413.
SpecificityRecognizes human DSG1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen


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