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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -DUSP2, CT (DUSP2, PAC1, Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1)

Anti -DUSP2, CT (DUSP2, PAC1, Dual specificity protein phosphatase 2, Dual specificity
protein phosphatase PAC-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B FC
DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Catalog #034857
ApplicationsSuitable for use in Western Blot, Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS NumberN/A
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
PurityPurified by ammonium sulfate precipitation
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 262-290 in the C-terminal region of human DUSP2, UniProt Accession #Q05923.
SpecificityRecognizes human DUSP2 at ~34kD.
Species CrossreactivityMouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDUSP2, PAC1, Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1


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