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034876 Rabbit Anti-DYRK1B, CT (DYRK1B, MIRK, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinase)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9Y463
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Gene ID
9149
Gene #
DYRK1B
Shipping Temp
Blue Ice
Storage Temp
-20°C
DYRK1B, MIRK, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinase

DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DYRK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567~597 amino acids from the C-terminal region of human DYRK1B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Human, mouse
References
Lim, S., et al., J. Biol. Chem. 277(51):49438-49445 (2002).|Lim, S., et al., J. Biol. Chem. 277(28):25040-25046 (2002).|Lee, K., et al., Cancer Res. 60(13):3631-3637 (2000).|Leder, S., et al., Biochem. Biophys. Res. Commun. 254(2):474-479 (1999).
USBio References
No references available
Conjugates
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