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You are here:Home » Antibodies » Abs to Hypoxia » Anti -EGLN2, ID (EGLN2, EIT6, Egl nine homolog 2, Estrogen-induced tag 6, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 1, Prolyl hydroxylase domain-containing protein 1) (FITC)

Anti -EGLN2, ID (EGLN2, EIT6, Egl nine homolog 2, Estrogen-induced tag 6, HPH-3,
Hypoxia-inducible factor prolyl hydroxylase 1, Prolyl hydroxylase domain-containing
protein 1) (FITC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH FC
EGLN2 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation.
Catalog #034970-FITC
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, FLISA
Recommended DilutionFLISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.
PurityPurified by Protein A affinity chromatography.
ImmunogenEGLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human EGLN2.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEGLN2, EIT6, Egl nine homolog 2, Estrogen-induced tag 6, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 1, Prolyl hydroxylase domain-containing protein 1


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