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034995 Rabbit Anti-EIF2C2, NT (Eif2c2, Ago2, Kiaa4215, Protein argonaute-2, Eukaryotic translation initiation factor 2C 2, Piwi/argonaute family protein meIF2C2, Protein slicer)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9UKV8
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
239528
Gene #
EIF2C2; Eif2c2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Eif2c2, Ago2, Kiaa4215, Protein argonaute-2, Eukaryotic translation initiation factor 2C 2, Piwi/argonaute family protein meIF2C2, Protein slicer

EIF2C2 is a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 27-59 in the N-terminal region of human EIF2C2, UniProt Accession #Q9UKV8. Species Sequence Homology: bovine, rabbit and rat
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human EIF2C2.
References
1. Rivas, F.V., et al., Nat Struct Mol Biol 12(4):340-349 (2005). 2. Liu, J., et al., Science 305(5689):1437-1441 (2004). 3. Nelson, P.T., et al., RNA 10(3):387-394 (2004). 4. Sasaki, T., et al., Genomics 82(3):323-330 (2003). 5. Doi, N., et al., Curr. Biol. 13(1):41-46 (2003).
USBio References
No references available
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