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You are here:Home » Antibodies » Abs to Receptors, Estrogen » Anti -ESR1 isoform1, CT (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1)

Anti -ESR1 isoform1, CT (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol
receptor, Nuclear receptor subfamily 3 group A member 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IF
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Catalog #035233
ApplicationsSuitable for use in Western Blot and Immunofluorescence (IC). Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Immunofluorescence (IC): 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa452-480 from the C-terminal region of human ESR1 isoform1, conjugated to KLH.
Species sequence homologyMouse, porcine, rat
SpecificityRecognizes human ESR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1


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