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You are here:Home » Antibodies » Abs to Receptors, Estrogen » Anti -ESR2, CT (ESR2, ESTRB, NR3A2, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2)

Anti -ESR2, CT (ESR2, ESTRB, NR3A2, Estrogen receptor beta, Nuclear receptor subfamily 3
group A member 2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Catalog #035239
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-527 amino acids from the C-terminal region of human ESR2.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesESR2, ESTRB, NR3A2, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2


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