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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -F11, ID (F11, Coagulation factor XI, Plasma thromboplastin antecedent, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain)

Anti -F11, ID (F11, Coagulation factor XI, Plasma thromboplastin antecedent, Coagulation
factor XIa heavy chain, Coagulation factor XIa light chain)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].
Catalog #035295
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-315 amino acids from the Central region of human F11.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesF11, Coagulation factor XI, Plasma thromboplastin antecedent, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain


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