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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -FBXO8, ID (FBXO8, FBS, FBX8, F-box only protein 8, F-box/SEC7 protein FBS)

Anti -FBXO8, ID (FBXO8, FBS, FBX8, F-box only protein 8, F-box/SEC7 protein FBS)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Catalog #035566
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenFBXO8 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 167-195 amino acids selected from the Central region of human FBXO8.
SpecificityMouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFBXO8, FBS, FBX8, F-box only protein 8, F-box/SEC7 protein FBS


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