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035765 Rabbit Anti-FRAT2, CT (FRAT2, GSK-3-binding protein FRAT2, Frequently rearranged in advanced T-cell lymphomas 2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IF IHC WB
Crossreactivity
Hu
Accession #
NP_036215.1; O75474
Gene ID
23401
Gene #
FRAT2
Shipping Temp
Blue Ice
Storage Temp
-20°C
FRAT2, GSK-3-binding protein FRAT2, Frequently rearranged in advanced T-cell lymphomas 2

The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Immunofluorescence: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-233 amino acids from the C-terminal region of human FRAT2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)|Liu, G.P., et al. Neurobiol. Aging 29(9):1348-1358(2008)|Stoothoff, W.H., et al. J. Biol. Chem. 280(1):270-276(2005)|Deloukas, P., et al. Nature 429(6990):375-381(2004)|Freemantle, S.J., et al. Gene 291 (1-2), 17-27 (2002) :
USBio References
No references available
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