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You are here:Home » Antibodies » Abs to Enzymes, Decarboxylase » Anti -GAD2, ID (GAD2, GAD65, Glutamate decarboxylase 2, 65kD glutamic acid decarboxylase, Glutamate decarboxylase 65kD isoform)

Anti -GAD2, ID (GAD2, GAD65, Glutamate decarboxylase 2, 65kD glutamic acid decarboxylase,
Glutamate decarboxylase 65kD isoform)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH IF
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Catalog #035868
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Immunofluorescence: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenGAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of human GAD2.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGAD2, GAD65, Glutamate decarboxylase 2, 65kD glutamic acid decarboxylase, Glutamate decarboxylase 65kD isoform


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