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036350 Rabbit Anti-GTD2A, CT (GTF2IRD2, GTF2IRD2A, General transcription factor II-I repeat domain-containing protein 2A, Transcription factor GTF2IRD2-alpha)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q86UP8
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Gene ID
84163
Gene #
GTF2IRD2
Shipping Temp
Blue Ice
Storage Temp
-20°C
GTF2IRD2, GTF2IRD2A, General transcription factor II-I repeat domain-containing protein 2A, Transcription factor GTF2IRD2-alpha

GTD2A is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. However, there is mRNA and EST evidence to suggest that this gene is transcribed, and the encoded protein has a homolog in mouse, with which it shares 78% sequence identity. The exact function of this gene product is not known. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. These three genes are clustered together on chr 7q11.23.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GTD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 820-850 from the C-terminal region of human GTD2A.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Hinsley, T.A., et al. Protein Sci. 13(10):2588-2599(2004)|Makeyev, A.V., et al. Proc. Natl. Acad. Sci. U.S.A. 101(30):11052-11057(2004)|Tipney, H.J., et al. Eur. J. Hum. Genet. 12(7):551-560(2004)
USBio References
No references available
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