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036477 Rabbit Anti-HDAC2, ID (HDAC2, Histone deacetylase 2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q92769
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IF IHC WB
Crossreactivity
Hu
Gene ID
3066
Gene #
HDAC2
Shipping Temp
Blue Ice
Storage Temp
-20°C
HDAC2, Histone deacetylase 2

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50 Immunofluorescence: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417~447 amino acids from the Central region of human HDAC2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Ishikawa, F., et al. Oncogene 29(6):909-919(2010)|Bush, E.W., et al. Circ. Res. 106(2):272-284(2010)|Krishnan, M., et al. Oncogene 29(2):305-312(2010)|Lehmann, A., et al. BMC Cancer 9, 395 (2009) |Hassig, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 95(7):3519-3524(1998)
USBio References
No references available
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