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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -HDAC3, CT (HDAC3, Histone deacetylase 3, RPD3-2, SMAP45)

Anti -HDAC3, CT (HDAC3, Histone deacetylase 3, RPD3-2, SMAP45)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
Catalog #036478
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenHDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-412 amino acids from the C-terminal region of human HDAC3.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHDAC3, Histone deacetylase 3, RPD3-2, SMAP45


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