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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -HERC3, NT (HERC3, KIAA0032, Probable E3 ubiquitin-protein ligase HERC3, HECT domain and RCC1-like domain-containing protein 3)

Anti -HERC3, NT (HERC3, KIAA0032, Probable E3 ubiquitin-protein ligase HERC3, HECT domain
and RCC1-like domain-containing protein 3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Catalog #036515
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenHERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHERC3, KIAA0032, Probable E3 ubiquitin-protein ligase HERC3, HECT domain and RCC1-like domain-containing protein 3


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