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036601 Rabbit Anti-HIST2H2AC, ID (HIST2H2AC, H2AFQ, Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q16777
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_003508.1
Gene ID
8338
Gene #
HIST2H2AC
Shipping Temp
Blue Ice
Storage Temp
-20°C
HIST2H2AC, H2AFQ, Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Ishibashi, T., et al. Biochemistry 48(22):5007-5017(2009)|Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39(3):251-262(2009)|Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) :|Guerrero-Santoro, J., et al. Cancer Res. 68(13):5014-5022(2008)|Zhao, Y., et al. Mol. Cell 29(1):92-101(2008)
USBio References
No references available
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