Anti -HSPA5, ID (HSPA5, GRP78, 78kD glucose-regulated protein, Endoplasmic reticulum
lumenal Ca(2+)-binding protein grp78, Heat shock 70kD protein 5, Immunoglobulin heavy
chain-binding protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH IF |
|
| When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell. | | | Catalog # | 036803 | | Applications | Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-500 | | Immunohistochemistry: 1:50-100 | | Immunofluorescence: 1:10-50 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the Central region of human HSPA5. | | Specificity | H,Z | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | HSPA5, GRP78, 78kD glucose-regulated protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70kD protein 5, Immunoglobulin heavy chain-binding protein |
External Links
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