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036817 Rabbit Anti-HSPH1, ID (HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105kD, Antigen NY-CO-25, Heat shock 110kD protein)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q92598
Isotype
IgG
Grade
Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
10808
Gene #
HSPH1
Shipping Temp
Blue Ice
Storage Temp
-20°C
HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105kD, Antigen NY-CO-25, Heat shock 110kD protein

HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 549-579 in the central region of human HSPH1. Species sequence homology: bovine, hamster, rat
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human HSPH1.
References
1. Ishihara K., Yasuda K., Hatayama T.Biochim. Biophys. Acta 1444:138-142(1999) 2. Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y.,DNA Res. 3:321-329(1996) 3. The MGC Project Team Genome Res. 14:2121-2127(2004) 4. Miyazaki M., Nakatsura T., Yokomine K., Senju S., Monji M., Hosaka S.,Cancer Sci. 96:695-705(2005)
USBio References
No references available
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