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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -INPP5B, CT (INPP5B, OCRL2, Type II inositol 1,4,5-trisphosphate 5-phosphatase, 75kD inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase)

Anti -INPP5B, CT (INPP5B, OCRL2, Type II inositol 1,4,5-trisphosphate 5-phosphatase, 75kD
inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].
Catalog #037054
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenINPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of human INPP5B.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesINPP5B, OCRL2, Type II inositol 1,4,5-trisphosphate 5-phosphatase, 75kD inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase


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