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You are here:Home » Antibodies » Abs to Interferon » Anti -IRF4, ID (IRF4, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, NF-EM5)

Anti -IRF4, ID (IRF4, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon
regulatory factor, Multiple myeloma oncogene 1, NF-EM5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B FC
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Catalog #037104
ApplicationsSuitable for use in Western Blot, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
ImmunogenIRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesIRF4, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, NF-EM5


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