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You are here:Home » Antibodies » Antibodies-Insulin » Anti -ISL1, ID (ISL1, Insulin gene enhancer protein ISL-1)

Anti -ISL1, ID (ISL1, Insulin gene enhancer protein ISL-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Catalog #037121
ApplicationsSuitable for use in Western Blot and ELISA Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 156-185 in the central region of human ISL1, UniProt Accession #P61371.
Species sequence homologyChicken, zebrafish, rat, rabbit
SpecificityRecognizes human ISL1. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesISL1, Insulin gene enhancer protein ISL-1


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