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037171-FITC Rabbit Anti-IZUM1, NT (IZUMO1, Izumo sperm-egg fusion protein 1, Oocyte binding/fusion factor, Sperm-specific protein izumo) (FITC)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8IYV9
Conjugate
FITC
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu
Accession #
NP_872381.2
Gene ID
284359
Gene #
IZUMO1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free
IZUMO1, Izumo sperm-egg fusion protein 1, Oocyte binding/fusion factor, Sperm-specific protein izumo

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).

Applications
Suitable for use in Western Blot and FLISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 77-105 from the N-terminal region of human IZUM1
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human IZUM1
References
1. Ellerman, D.A., et al. Mol. Reprod. Dev. 76(12):1188-1199(2009). 2. Inoue, N., et al. Biochem. Biophys. Res. Commun. 377(3):910-914(2008). 3. Granados-Gonzalez, V., et al. Fertil. Steril. 90(4):1246-1248(2008). 4. Yatsenko, A.N., et al. Hum. Mol. Genet. 15(23):3411-3419(2006). 5. Inoue, N., et al. Nature 434(7030):234-238(2005).
USBio References
No references available
Conjugates
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