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037264 Rabbit Anti-Kallikrein 7, CT (KLK7, PRSS6, SCCE, Kallikrein-7, Serine protease 6, Stratum corneum chymotryptic enzyme)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P49862
Isotype
IgG
Grade
Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
5650
Gene #
KLK7
Shipping Temp
Blue Ice
Storage Temp
-20°C
KLK7, PRSS6, SCCE, Kallikrein-7, Serine protease 6, Stratum corneum chymotryptic enzyme

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK7 enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-100 Immunohistochemistry: 1:10-50 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Kallikrein 7 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165~194 amino acids from the C-terminal region of human KLK7.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Human
References
Planque, C., et al., Biochem. Biophys. Res. Commun. 329(4):1260-1266 (2005).|Ishida-Yamamoto, A., et al., J. Invest. Dermatol. 124(2):360-366 (2005).|Vasilopoulos, Y., et al., J. Invest. Dermatol. 123(1):62-66 (2004).|Santin, A.D., et al., Gynecol. Oncol. 94(2):283-288 (2004).|Caubet, C., et al., J. Invest. Dermatol. 122(5):1235-1244 (2004).
USBio References
No references available
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