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You are here:Home » Antibodies » Abs to Leptin » Anti -LEP, NT (LEP, OB, OBS, Leptin, Obese Protein, Obesity Factor) (PE)

Anti -LEP, NT (LEP, OB, OBS, Leptin, Obese Protein, Obesity Factor) (PE)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH FC IF
Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in the gene encoding this protein and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. The gene has also been linked to type 2 diabetes mellitus development [provided by RefSeq].
Catalog #037738-PE
ApplicationsSuitable for use in FLISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (R-PE).
PurityPurified by Protein A affinity chromatography
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 8-37 in the N-terminal region of human LEP, UniProt Accession #P41159.
Species Sequence HomologyMouse
SpecificityRecognizes human LEP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesLEP, OB, OBS, Leptin, Obese protein, Obesity factor


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