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037929 Rabbit Anti-LRIG1, CT (LRIG1, LIG1, Leucine-rich repeats and immunoglobulin-like domains protein 1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Swiss Prot
Q96JA1
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Mo
Accession #
NP_056356.2
Gene ID
26018
Gene #
LRIG1
Shipping Temp
Blue Ice
Storage Temp
-20°C
LRIG1, LIG1, Leucine-rich repeats and immunoglobulin-like domains protein 1

LRIG1 act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
LRIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 801-829 amino acids from the C-terminal region of human LRIG1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :|Ye, F., et al. J. Neurooncol. 94(2):183-194(2009)|Ljuslinder, I., et al. Breast Cancer Res. 11 (3), 403 (2009) :|Miller, J.K., et al. Cancer Res. 68(20):8286-8294(2008)|Stutz, M.A., et al. Oncogene 27(43):5741-5752(2008)
USBio References
No references available
Conjugates
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