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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -MARCH4, CT (MARCH4, KIAA1399, RNF174, E3 ubiquitin-protein ligase MARCH4, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174)

Anti -MARCH4, CT (MARCH4, KIAA1399, RNF174, E3 ubiquitin-protein ligase MARCH4,
Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING
finger protein 174)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).
Catalog #038195
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMARCH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of human MARCH4.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMARCH4, KIAA1399, RNF174, E3 ubiquitin-protein ligase MARCH4, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174


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