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You are here:Home » Antibodies » Abs to Cancer Markers, Leukemia » Anti -MCL1, BH3 Domain Specific (MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT)

Anti -MCL1, BH3 Domain Specific (MCL1, BCL2L3, Induced myeloid leukemia cell
differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1,
mcl1/EAT)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IH FC
The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Catalog #038275
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation
ImmunogenSynthetic peptide corresponding to aa191-226 from human Mcl-1, conjugatd to KLH (Q07820)
SpecificityRecognizes human Mcl-1 at ~37kD. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT


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