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038400 Rabbit Anti-MFRN2, NT (SLC25A28, MFRN2, Mitoferrin-2, Mitochondrial RNA-splicing protein 3/4 homolog, Mitochondrial iron transporter 2, Solute carrier family 25 member 28)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q96A46
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
81894
Gene #
SLC25A28
Shipping Temp
Blue Ice
Storage Temp
-20°C
SLC25A28, MFRN2, Mitoferrin-2, Mitochondrial RNA-splicing protein 3/4 homolog, Mitochondrial iron transporter 2, Solute carrier family 25 member 28

MFRN2 is mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MFRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-74 amino acids from the N-terminal region of human MFRN2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)|Deloukas, P., et al. Nature 429(6990):375-381(2004)|Wistow, G., et al. Mol. Vis. 8, 185-195 (2002)
USBio References
No references available
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