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You are here:Home » Antibodies » Abs to Transcription Factors, TRIM (Tripartite Motif) » Anti -MID1, CT (MID1, FXY, RNF59, TRIM18, XPRF, Midline-1, Midin, Midline 1 RING finger protein, Putative transcription factor XPRF, RING finger protein 59, Tripartite motif-containing protein 18) (APC)

Anti -MID1, CT (MID1, FXY, RNF59, TRIM18, XPRF, Midline-1, Midin, Midline 1 RING finger
protein, Putative transcription factor XPRF, RING finger protein 59, Tripartite
motif-containing protein 18) (APC)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however, the full-length nature of some of the variants has not been determined.
Catalog #038427-APC
ApplicationsSuitable for use in Western Blot, FLISA
Recommended DilutionFLISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note Applications are based on unconjugated antibody.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).
PurityPurified by Protein A affinity chromatography.
ImmunogenMID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574-603 amino acids from the C-terminal region of human MID1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMID1, FXY, RNF59, TRIM18, XPRF, Midline-1, Midin, Midline 1 RING finger protein, Putative transcription factor XPRF, RING finger protein 59, Tripartite motif-containing protein 18


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