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Anti -MLF1, CT (MLF1, Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1)
Anti -MLF1, CT (MLF1, Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH FC |
|
| MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. | | | Catalog # | 038463 | | Applications | Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-500 | | Flow Cytometry: 1:10-50 | | Immunohistochemistry: 1:10-50 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222~252 amino acids from the C-terminal region of human MLF1. | | Specificity | Human, mouse | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | MLF1, Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1 |
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