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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -MLH1, CT (DNA mismatch repair protein Mlh1, MutL protein homolog 1, COCA2, MLH1)

Anti -MLH1, CT (DNA mismatch repair protein Mlh1, MutL protein homolog 1, COCA2, MLH1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). The protein is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
Catalog #038467
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
ImmunogenMLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human MLH1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDNA mismatch repair protein Mlh1, MutL protein homolog 1, COCA2, MLH1


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