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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP17, CT (MMP17, MT4MMP, Matrix metalloproteinase-17, Membrane-type matrix metalloproteinase 4, Membrane-type-4 matrix metalloproteinase)

Anti -MMP17, CT (MMP17, MT4MMP, Matrix metalloproteinase-17, Membrane-type matrix
metalloproteinase 4, Membrane-type-4 matrix metalloproteinase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Catalog #038505
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMMP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-460 amino acids from the C-terminal region of human MMP17.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMMP17, MT4MMP, Matrix metalloproteinase-17, Membrane-type matrix metalloproteinase 4, Membrane-type-4 matrix metalloproteinase


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