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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP2, ID (MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX)

Anti -MMP2, ID (MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A,
Matrix metalloproteinase-2, TBE-1, PEX)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Catalog #038507
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the Central region of human MMP2.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX


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