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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP20, CT (MMP20, Matrix metalloproteinase-20, Enamel metalloproteinase, Enamelysin)

Anti -MMP20, CT (MMP20, Matrix metalloproteinase-20, Enamel metalloproteinase, Enamelysin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes that localizes to chromosome 11q22.3.
Catalog #038508
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMMP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-428 amino acids from the C-terminal region of human MMP20.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMMP20, Matrix metalloproteinase-20, Enamel metalloproteinase, Enamelysin


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