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038560 Rabbit Anti-MPI, NT (MPI, PMI1, Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P34949
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_002426.1
Gene ID
4351
Gene #
MPI
Shipping Temp
Blue Ice
Storage Temp
-20°C
MPI, PMI1, Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human MPI.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Xiao, J., et al. J. Mol. Graph. Model. 25(3):289-295(2006)|Vuillaumier-Barrot, S., et al. J. Med. Genet. 39(11):849-851(2002)|Schollen, E., et al. Eur. J. Hum. Genet. 10(10):643-648(2002)
USBio References
No references available
Conjugates
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