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You are here:Home » Antibodies » Abs to Mitochondrial Proteins » Anti -MRPL40, CT (MRPL40, NLVCF, URIM, 39S ribosomal protein L40, mitochondrial, Nuclear localization signal-containing protein deleted in velocardiofacial syndrome, Up-regulated in metastasis)

Anti -MRPL40, CT (MRPL40, NLVCF, URIM, 39S ribosomal protein L40, mitochondrial, Nuclear
localization signal-containing protein deleted in velocardiofacial syndrome, Up-regulated
in metastasis)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
Catalog #038596
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMRPL40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human MRPL40.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMRPL40, NLVCF, URIM, 39S ribosomal protein L40, mitochondrial, Nuclear localization signal-containing protein deleted in velocardiofacial syndrome, Up-regulated in metastasis


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